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2016, № 60

UDC: 602.4:582.929
GSNTI: 62.33.29

Biotechnological techniques of cultivating Coleus blumei Benth.

Secondary metabolites of plants have wide range of biological activities and may be used in pharmaceutical, food and perfume-cosmetic industries. Cultivating medicine plants in vitro with the aim of secondary metabolites production has advantages compared with traditional ways. Isolated plants’ tissues and cells yield often much more secondary metabolites than intact plants. Plants of species Coleus blumei Benth. are commercial source of rosmarinic acid. This valuable secondary metabolite possesses antiallergenic, antioxidant, anti-inflammatory, antiviral, antibacterial and binding activities and is used in medicine. Moreover, rosmarinic acid is used in medicine for Herpes simplex, as putative anticancer drug and potential preservative. Biotechnological methods allow getting a large amount of rosmarinic acid in a short time using suspension culture or hairy roots. Optimization of micropropagation methods and use of new, unusual cultivating techniques may ease extraction of rosmarinic acid from intracellular and cultivating medium. This review covers a wide range of biotechnological researches of Coleus blumei Benth.
Keywords: Secondary metabolism, clonal micropropagation, Coleus blumei, Lamiaceae, in vitro culture

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Authors:

1. Ermolaev Alexey Sergeevich, BSc student, Federal State Budgetary Educational Institute of Higher Education “Russian Timiryazev State Agrarian University”.
2. Cherednichenko Mikhail Yuryevich, PhD in Biotechnology, associate professor, Department of Genetics, Biotechnology, Plant Breeding and Seed Science, Federal State Budgetary Educational Institute of Higher Education “Russian Timiryazev State Agrarian University”.